The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2020

Filed:

Feb. 27, 2018
Applicant:

St. Jude Medical, Cardiology Division, Inc., St. Paul, MN (US);

Inventor:

Paul E. Ashworth, Wyoming, MN (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/564 (2006.01); G01N 1/30 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
G01N 33/564 (2013.01); A61K 35/12 (2013.01); G01N 1/30 (2013.01); G01N 2001/305 (2013.01); G01N 2333/4716 (2013.01);
Abstract

Methods of preparing a solid reference material so as to elicit a positive control response when tested for in-vitro complement activation include providing biological tissue; treating the tissue with an aqueous cellulose solution for a time sufficient to allow fluid in the tissue to be replaced by the aqueous cellulose solution; drying the cellulose-treated tissue by a vacuum-drying process or a lyophilization process to form dried tissue; and storing the dried tissue in a dry, ambient environment. The tissue prepared by these methods and its use in an in-vitro complement assay and diagnostic kit are also described.


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