The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2020

Filed:

May. 11, 2018
Applicant:

Bio-rad Laboratories, Inc., Hercules, CA (US);

Inventors:

Xiao-Song Gong, Berkeley, CA (US);

John Sullivan, Oakland, CA (US);

Rongdian Fu, El Cerrito, CA (US);

Yan Wang, San Francisco, CA (US);

Evan H. Bursey, Concord, CA (US);

Man Cheng, San Ramon, CA (US);

Assignee:

Bio-Rad Laboratories, Inc., Hercules, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 19/00 (2006.01); C12Q 1/6804 (2018.01); C12Q 1/686 (2018.01); C12P 19/34 (2006.01); C07K 16/40 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C12P 19/34 (2013.01); C07K 16/40 (2013.01); C12N 9/1252 (2013.01); C12Q 1/6804 (2013.01); C12Q 1/686 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2319/80 (2013.01);
Abstract

The present invention provides methods and compositions for improving the efficiency of nucleic acid amplification reactions. The invention encompasses hybrid polymerases that show increased processivity over wild type polymerases as well as decreased exonucleases activity. The invention also encompasses methods, compositions and kits for conducting nucleic acid synthesis and amplification reactions in which non-specific amplification of primers is reduced.


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