The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2020

Filed:

Jan. 29, 2016
Applicant:

University of Massachusetts, Boston, MA (US);

Inventors:

Vincent M. Rotello, Amherst, MA (US);

Rubul Mout, Amherst, MA (US);

Assignee:

University of Massachusetts, Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 17/14 (2006.01); A61K 47/69 (2017.01); C12N 9/12 (2006.01); C12N 9/22 (2006.01); C12N 9/64 (2006.01); C12N 9/96 (2006.01); C12N 15/113 (2010.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C07K 17/14 (2013.01); A61K 47/6923 (2017.08); C12N 9/1241 (2013.01); C12N 9/22 (2013.01); C12N 9/6467 (2013.01); C12N 9/96 (2013.01); C12N 15/113 (2013.01); C12N 15/907 (2013.01); C12Y 304/21078 (2013.01); C12N 2310/20 (2017.05);
Abstract

Various embodiments disclosed relate to a nanoparticle-protein complex for intracellular protein delivery. In various embodiments, the present invention provides a nanoparticle-protein complex including a nanoparticle including an amine-containing ligand. The nanoparticle-protein complex also includes a protein comprising a carboxylic acid-containing tag.


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