The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2020
Filed:
Mar. 04, 2016
Applicant:
Igm Biosciences, Inc., Mountain View, CA (US);
Inventors:
Bruce Alan Keyt, Hillsborough, CA (US);
Omar Duramad, Berkley, CA (US);
Beatrice Tien-Yi Wang, Mountain View, CA (US);
Ramesh Baliga, Redwood City, CA (US);
Fen Zhang, San Francisco, CA (US);
Assignee:
IGM Biosciences, Inc., Mountain View, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61P 35/02 (2006.01); A61K 48/00 (2006.01); C12N 15/62 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2887 (2013.01); A61K 48/00 (2013.01); A61P 35/02 (2018.01); C07K 16/2809 (2013.01); C12N 15/62 (2013.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01); C07K 2317/35 (2013.01); C07K 2317/52 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/734 (2013.01); C07K 2319/00 (2013.01); C07K 2319/035 (2013.01); C07K 2319/33 (2013.01);
Abstract
This disclosure provides pentameric and hexameric CD20 binding molecules and methods of using such molecules to direct complement-mediated, T-cell-mediated, or both complement-mediated and T-cell-mediated killing of CD20-expressing cells.