The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2020
Filed:
Dec. 18, 2015
Applicants:
The Johns Hopkins University, Baltimore, MD (US);
St. Jude's Children's Research Hospital Inc., Memphis, TN (US);
Inventors:
Drew M. Pardoll, Brookeville, MD (US);
Ching-Tai Huang, Taipei, TW;
Jonathan Powell, Baltimore, MD (US);
Charles Drake, Baltimore, MD (US);
Dario A. Vignali, Pittsburgh, PA (US);
Creg J. Workman, Memphis, TN (US);
Assignees:
The Johns Hopkins University, Baltimore, MD (US);
St. Jude's Children's Research Hospital, Inc., Memphis, TN (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A01K 67/027 (2006.01); A61K 39/00 (2006.01); C07K 14/705 (2006.01); C12N 5/0783 (2010.01); A61K 39/395 (2006.01); C07K 16/42 (2006.01); C07K 16/18 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A01K 67/0271 (2013.01); A01K 67/0276 (2013.01); A61K 39/0011 (2013.01); A61K 39/3955 (2013.01); A61K 39/39558 (2013.01); C07K 14/70503 (2013.01); C07K 16/18 (2013.01); C07K 16/42 (2013.01); C12N 5/0636 (2013.01); A01K 2267/0381 (2013.01); A61K 2035/122 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/55516 (2013.01); C12N 2501/599 (2013.01); C12N 2510/00 (2013.01); C12N 2799/027 (2013.01);
Abstract
Anti-CD223 antibodies overcome immune suppression in cancer patients. The anti-CD223 antibodies may be generated in an animal by injection of fragments of CD223. Antibodies may be monoclonal antibodies or single chain antibodies or humanized antibodies.