The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2020

Filed:

Oct. 21, 2016
Applicant:

Takeda Pharmaceutical Company Limited, Osaka-shi, Osaka, JP;

Inventors:

Takatoshi Yogo, Fujisawa, JP;

Masato Yoshikawa, Fujisawa, JP;

Morihisa Saitoh, Fujisawa, JP;

Taisuke Katoh, Fujisawa, JP;

Tomohiro Seki, Fujisawa, JP;

Yoshihisa Nakada, Fujisawa, JP;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); C07D 487/04 (2006.01); C07D 471/04 (2006.01); C07D 513/04 (2006.01); A61K 31/55 (2006.01); A61K 31/553 (2006.01); A61K 31/554 (2006.01); A61P 31/12 (2006.01); A61P 13/12 (2006.01); A61P 1/16 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61K 31/55 (2013.01); A61K 31/553 (2013.01); A61K 31/554 (2013.01); A61P 1/16 (2018.01); A61P 13/12 (2018.01); A61P 25/00 (2018.01); A61P 31/12 (2018.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 513/04 (2013.01);
Abstract

The present invention provides a heterocyclic compound having an RIP1 kinase inhibitory action, which is useful for the prophylaxis or treatment of Gaucher's disease, Niemann-Pick disease, inflammatory bowel disease, multiple sclerosis, chronic kidney disease, acute kidney injury, acute hepatic failure, autoimmune hepatitis, hepatitis B, hepatitis C, alcohol steatohepatitis, non-alcohol steatohepatitis and the like. The present invention relates to a compound represented by the following formula (I): wherein each symbol is as defined in the specification, or a salt thereof.


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