The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2020

Filed:

Nov. 13, 2017
Applicants:

Jiangsu Hengrui Medicine Co., Ltd., Lianyungang, Jiangsu, CN;

Suncadia Pharmaceuticals Co., Ltd., Chengdu, Sichuan, CN;

Inventors:

Quanliang Zhang, Jiangsu, CN;

Junlei Jia, Jiangsu, CN;

Lin Bian, Jiangsu, CN;

Xiaohui Gao, Jiangsu, CN;

Assignees:

Jiangsu Hengrui Medicine Co., Ltd., Lianyungang, Jiangsu, CN;

Suncadia Pharmaceuticals Co., Ltd., Chengdu, Sichuan, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 473/28 (2006.01); C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 15/00 (2006.01);
U.S. Cl.
CPC ...
C07D 473/28 (2013.01); A61K 31/519 (2013.01); A61P 15/00 (2018.01); C07D 487/04 (2013.01); C07B 2200/13 (2013.01);
Abstract

Provided are a crystalline form of a GnRH receptor antagonist and a preparation method therefor. Specifically, provided are a crystalline form I of 1-(4-(7-(2,6-difluorobenzyl)-3-((dimethylamino)methyl)-5-(6-methoxypyridazin-3-yl)-4,6-dicarbonyl-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-2-yl)phenyl)-3-methoxy urea (a compound of formula I) and a preparation method, the use of same in a pharmaceutical composition and the use of the crystalline form I and the composition in the preparation of a drug for treating diseases associated with a GnRH receptor antagonist.


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