The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2020
Filed:
Aug. 09, 2017
University of Kansas, Lawrence, KS (US);
The Regents of the University of Michigan, Ann Arbor, MI (US);
Wayne State University, Detroit, MI (US);
Sanford-burnham Medical Research Institute, La Jolla, CA (US);
Jennifer E. Golden, Olathe, KS (US);
Jeffrey Aube, Lawrence, KS (US);
Daniel P. Flaherty, Overland Park, KS (US);
Andrew M. Fribley, Brighton, MI (US);
Randal J. Kaufman, San Diego, CA (US);
Thomas D. Y. Chung, Carlsbad, CA (US);
Anthony B. Pinkerton, San Diego, CA (US);
Michael Pablo Hedrick, Carlsbad, CA (US);
UNIVERSITY OF KANSAS, Lawrence, KS (US);
THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);
SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE, La Jolla, CA (US);
WAYNE STATE UNIVERSITY, Detroit, MI (US);
Abstract
N-substituted sulfonylphenyl-5-nitrofuranyl-2-carboxamide derived compounds, which selectively activate the apoptotic, but not the adaptive arm, of the Unfolded Protein Response are provides as is their use in the treatment of diseases such as diabetes, Alzheimer's, Parkinson's, hemophilia, lysosomal storage diseases and cancer.