The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2020

Filed:

Feb. 27, 2018
Applicants:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Janssen Biotech, Inc., Horsham, PA (US);

Inventors:

Maria P. Limberis, Philadelphia, PA (US);

Anna P. Tretiakova, Woburn, MA (US);

James M. Wilson, Philadelphia, PA (US);

Michael Naso, Swarthmore, PA (US);

Joost Kolkman, Maarn, NL;

Robert Friesen, Wassenaar, NL;

Qiang Wang, Philadelphia, PA (US);

Assignees:

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Janssen Biotech, Inc., Horsham, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/42 (2006.01); A61K 39/145 (2006.01); C07K 16/10 (2006.01); C12N 7/06 (2006.01); A61P 31/16 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/42 (2013.01); A61K 39/145 (2013.01); A61P 31/16 (2018.01); C07K 16/1018 (2013.01); C12N 7/00 (2013.01); C12N 7/06 (2013.01); A61K 2039/505 (2013.01); A61K 2039/5256 (2013.01); C07K 2317/31 (2013.01); C07K 2317/52 (2013.01); C07K 2317/569 (2013.01); C12N 2750/14121 (2013.01); C12N 2750/14143 (2013.01); C12N 2840/203 (2013.01);
Abstract

A non-replicating recombinant adeno-associated associated virus (rAAV) having an AAV capsid having packaged therein a vector genome which comprises AAV inverted terminal repeat sequences and at least one nucleic acid sequence encoding four different immunoglobulin regions (a), (b), (c) and (d) is provided. The rAAV-expressed immunoglobulins are useful for providing passive immunization against influenza A and influenza B. Also described herein are compositions containing the rAAV. Methods of vaccinating patients against influenza are provided.


Find Patent Forward Citations

Loading…