The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2020
Filed:
May. 08, 2019
Applicants:
The Trustees of Princeton University, Princeton, NJ (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
Inventors:
Yibin Kang, Princeton, NJ (US);
Yongna Xing, Middleton, WI (US);
Liling Wan, Princeton, NJ (US);
Feng Guo, Sunnyvale, CA (US);
Assignees:
The Trustees of Princeton University, Princeton, NJ (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/82 (2006.01); A61K 38/17 (2006.01); A61K 38/08 (2019.01); C07K 14/47 (2006.01); A61K 38/10 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); A61K 38/08 (2013.01); A61K 38/10 (2013.01); A61P 35/00 (2018.01); C07K 14/4748 (2013.01); C07K 14/82 (2013.01);
Abstract
The present disclosure related in general to methods of treating cancer by interfering with the interaction of metadherin with Staphylococcal nuclease domain-containing 1 (SND1) using peptides or other compounds that inhibit the binding of SND1 with metadherin and inhibit the activity of the MTDH-SND1 complex in tumor cells.