The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2020
Filed:
Feb. 06, 2018
Applicant:
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Alexander Muir, Cambridge, MA (US);
Matthew Vander Heiden, Cambridge, MA (US);
Laura Danai, Brighton, MA (US);
Dan Yi Gui, Cambridge, MA (US);
Assignee:
Massachusetts Institute of Technology, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/198 (2006.01); A61K 31/554 (2006.01); A61K 9/00 (2006.01); A61K 31/225 (2006.01); A61K 45/06 (2006.01); A61K 31/277 (2006.01); A61K 31/7105 (2006.01); A61K 38/17 (2006.01); G01N 33/68 (2006.01); A61P 35/00 (2006.01); A61K 31/69 (2006.01); A61K 31/501 (2006.01); A61K 31/255 (2006.01); A61K 45/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61K 9/0053 (2013.01); A61K 31/225 (2013.01); A61K 31/255 (2013.01); A61K 31/277 (2013.01); A61K 31/501 (2013.01); A61K 31/554 (2013.01); A61K 31/69 (2013.01); A61K 31/7105 (2013.01); A61K 38/1709 (2013.01); A61K 45/00 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); G01N 33/6893 (2013.01); G01N 2333/47 (2013.01);
Abstract
The invention relates to methods and related compositions for enhancing cancer therapy and in particular glutaminase inhibitor therapy. The methods involve methods for identifying patients susceptible to glutaminase inhibitor therapy as well as sensitizing patients to glutaminase inhibitor therapy.