The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 2020
Filed:
Jan. 03, 2018
Applicant:
Incelldx, Inc., Menlo Park, CA (US);
Inventors:
Bruce K. Patterson, Palo Alto, CA (US);
Amanda Noel Chargin, San Jose, CA (US);
Keith Shults, Nolensville, TN (US);
Assignee:
IncellDx, Inc., San Carlos, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); G01N 15/14 (2006.01); G01N 1/30 (2006.01); C12Q 1/6881 (2018.01); C12Q 1/6886 (2018.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57423 (2013.01); C12Q 1/6881 (2013.01); C12Q 1/6886 (2013.01); G01N 1/30 (2013.01); G01N 15/14 (2013.01); G01N 15/1456 (2013.01); G01N 33/57492 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1486 (2013.01); G01N 2333/70532 (2013.01); G01N 2800/52 (2013.01);
Abstract
Methods are provided for detecting the per cell programmed-death ligand 1 (PD-L1) expression of neoplasia cells. Aspects of the methods include cytometrically assaying a labeled cell suspension to quantify per cell PD-L1 expression to detect whether a neoplastic cell that expresses PD-L1 above a predetermined threshold is present in the neoplasia sample. In addition, kits that find use in practicing the subject methods are also provided.