The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 2020
Filed:
Apr. 02, 2015
Applicant:
Marshall University Research Corportion, Huntington, WV (US);
Inventors:
Zijian Xie, Huntington, WV (US);
Moumita Banerjee, Huntington, WV (US);
Assignee:
MARSHALL UNIVERSITY RESEARCH CORPORATION, Huntington, WV (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C12N 9/14 (2006.01); C12Q 1/50 (2006.01); C12Q 1/48 (2006.01); G01N 33/573 (2006.01); G01N 33/50 (2006.01); C07K 7/08 (2006.01); A61K 38/46 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C12N 9/14 (2013.01); A61K 38/46 (2013.01); A61K 45/06 (2013.01); C07K 7/08 (2013.01); C12Q 1/485 (2013.01); C12Q 1/50 (2013.01); C12Y 306/03009 (2013.01); G01N 33/5044 (2013.01); G01N 33/573 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/01 (2013.01); G01N 2333/3153 (2013.01); G01N 2333/3156 (2013.01); G01N 2333/91 (2013.01); G01N 2333/9723 (2013.01);
Abstract
Non-naturally occurring peptides are provided that act as a Src SH2 domain antagonist of cardiotonic steroids. Pharmaceutical compositions comprising the peptides are also provided along with vectors encoding the peptides. Methods of treating a Src-associated disease and reducing Src activity in a cell are further provided and include administering or contacting a cell with an effective amount of the peptide.