The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 2020
Filed:
Oct. 19, 2017
Applicants:
Texas State University, San Marcos, TX (US);
Leiden University, Leiden, NL;
Inventors:
Alexander Kornienko, San Marcos, TX (US);
Tania Betan-Court, San Marcos, TX (US);
Sylvestre Bonnet, Amsterdam, NL;
Vincent Van Rixel, Amsterdam, NL;
Assignees:
Texas State University, San Marcos, TX (US);
Leiden University, Leiden, NL;
Primary Examiner:
Int. Cl.
CPC ...
C07F 15/00 (2006.01);
U.S. Cl.
CPC ...
C07F 15/00 (2013.01);
Abstract
Described herein is photocaging methodology using ruthenium (II) complexes with 7-deazahypoxanthine-based anticancer agents. Specifically, 7-deazahypoxanthines are converted into photoactivatable chemotherapeutic agents for the controlled release of these toxic agents selectively into tumor tissue upon irradiation with light.