The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 22, 2020

Filed:

Dec. 27, 2016
Applicant:

Precedo Pharmaceuticals Co., Ltd, Hefei, Anhui, CN;

Inventors:

Qingsong Liu, Anhui, CN;

Jing Liu, Anhui, CN;

Xixiang Li, Anhui, CN;

Aoli Wang, Anhui, CN;

Hong Wu, Anhui, CN;

Kailin Yu, Anhui, CN;

Chen Hu, Anhui, CN;

Wenchao Wang, Anhui, CN;

Cheng Chen, Anhui, CN;

Fengming Zou, Anhui, CN;

Ziping Qi, Anhui, CN;

Li Wang, Anhui, CN;

Beilei Wang, Anhui, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/519 (2013.01); A61P 35/00 (2018.01);
Abstract

The present application provides a compound of Formula (I) as an inhibitor against wild-type EGFR and/or mutant EGFR, which may be used for treating human non-small cell lung cancer individually or in combination with other therapeutic agent(s). The compound of Formula (I) of the present application may be used for treating patients of drug-resistant human non-small cell lung cancer harboring wild-type EGFR and/or EGFR T790M mutation and/or EGFR L858R mutation and/or EGFR delE746_A750 mutation.


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