The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 2020
Filed:
Dec. 05, 2017
Applicant:
Glactone Pharma Development Ab, Helsingborg, SE;
Inventors:
Martin Johansson, Helsingborg, SE;
Olov Sterner, Malmö, SE;
Assignee:
GLACTONE PHARMA DEVELOPMENT AB, Helsingborg, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/93 (2006.01); C07D 401/12 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); A61K 31/365 (2006.01); A61K 31/422 (2006.01); A61K 31/443 (2006.01); A61K 45/06 (2006.01); A61K 31/381 (2006.01);
U.S. Cl.
CPC ...
C07D 307/93 (2013.01); A61K 31/365 (2013.01); A61K 31/381 (2013.01); A61K 31/422 (2013.01); A61K 31/443 (2013.01); A61K 45/06 (2013.01); C07D 401/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01);
Abstract
Disclosed are sulfonamide analogues of galiellactone of formula (I) as STAT3-inhibitors for use in the treatment of a STAT3 signaling related disorder, e.g. solid cancers, hematological cancers, benign tumors, hyperproliferative diseases, inflammations, autoimmune diseases, graft or transplant rejections, delayed physiological function of grafts or transplants, neurodegenerative diseases and viral infections. The sulfonamide comprises a cyclic substituent.