The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 22, 2020

Filed:

May. 08, 2017
Applicant:

Novintethical Pharma SA, Lugano, CH;

Inventors:

Miguel Angel Alonso Cohen, Barcelona, ES;

Marco Di Fulvio, Soriano Nel Cimino, IT;

Assignee:

DEVINTEC SAGL, Lugano, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); C07K 1/107 (2006.01); A61K 47/61 (2017.01); A61K 47/64 (2017.01); A61K 38/01 (2006.01); A61P 29/00 (2006.01); A61P 1/04 (2006.01); A61P 35/00 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/168 (2013.01); A61K 9/0053 (2013.01); A61K 38/01 (2013.01); A61K 38/011 (2013.01); A61K 47/61 (2017.08); A61K 47/64 (2017.08); A61P 1/04 (2018.01); A61P 29/00 (2018.01); A61P 35/00 (2018.01); C07K 1/1077 (2013.01);
Abstract

The invention provides a process for preparing a protein-polysaccharide conjugated product comprising: (a) preparing a mixture comprising pea protein, polysaccharide, and an appropriate polar solvent; wherein: the weight ratio between polysaccharide and protein is comprised from 20:80 to 60:40, and the pH of the solution is comprised from 8.0 to 10.5; and performing a Maillard reaction by heating the solution resulting from step (a) at an appropriate temperature for the necessary period of time to conjugate the protein and the polysaccharide. The invention further provides a conjugated product obtainable by the process of the invention, as well as pharmaceutical compositions comprising the conjugate and to their use in the treatment in gastrointestinal disorders. The conjugate of the invention shows a remarkable improvement in preventing and/or treating intestinal diseases, such as mucositis.


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