The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 22, 2020

Filed:

May. 22, 2018
Applicant:

Can-fite Biopharma Ltd., Petach Tikva, IL;

Inventors:

Pnina Fishman, Petach Tikva, IL;

Shira Cohen, Hod Hasharon, IL;

Assignee:

CAN-FITE BIOPHARMA LTD., Petach Tikva, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7076 (2006.01); A61P 1/16 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7076 (2013.01); A61K 9/0053 (2013.01); A61P 1/16 (2018.01);
Abstract

Provided is an AAR ligand for reducing ectopic fat accumulation, particularly in fatty liver. Further provided is the use of AAR ligand for the preparation of a pharmaceutical composition for reducing such fat accumulation, method of treating a condition associates with fat accumulation making use of the ligand and kits including pharmaceutical compositions including the ligand, and instructions for use of same, for treating a condition associated with ectopic fat accumulation. Further provided is the use of an AAR agonist, such as 2-Chloro-N-(3-iodobenzyl)-adenosine-5'-N-methyluronamide (Cl-IB-MECA, CF102) for treating fatty liver, specifically, non-alcoholic fatty liver disease (NAFLD).


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