The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 2020
Filed:
Nov. 25, 2015
Applicants:
Adc Therapeutics SA, Epalinges, CH;
Medimmune Limited, Cambridge, Cambridgeshire, GB;
Inventors:
Patricius Henrikus Cornelis Van Berkel, Epalinges, CH;
Philip Wilson Howard, Cambridge, GB;
John Hartley, London, GB;
Assignees:
ADC THERAPEUTICS SA, Epalinges, CH;
MEDIMMUNE LIMITED, Cambridge, Cambridgesh, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5517 (2006.01); A61K 47/68 (2017.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5517 (2013.01); A61K 47/6803 (2017.08); A61K 47/6849 (2017.08); A61K 47/6889 (2017.08); C07K 16/2866 (2013.01); C07K 2317/21 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present disclosure relates to the use of antibody-drug conjugates (ADCs) comprising pyrrolobenzodiazepine (PBD) dimers and anti-CD25 antibodies for use in treating disorders characterized by the presence of CD25+ve cells.