The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 22, 2020
Filed:
Oct. 07, 2015
Applicant:
Albert Einstein College of Medicine, Bronx, NY (US);
Inventors:
Samantha E. Wilner, Bronx, NY (US);
Matthew Levy, New Rochelle, NY (US);
Assignee:
Albert Einstein College of Medicine, Bronx, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 9/107 (2006.01); A61K 47/69 (2017.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
A61K 9/107 (2013.01); A61K 47/26 (2013.01); A61K 47/6907 (2017.08); A61K 9/1075 (2013.01);
Abstract
Methods and compositions for serum-stabilizing micelles for drug delivery or imaging agent delivery are provided, as well as methods and compositions to enhance micelle-mediated drug delivery. This invention provides a process for synthesizing a lipid micelle comprising one or more lipid-oligonucleotide conjugate molecules, the process comprising contacting an amount of lipid molecules with an amount of lipid-oligonucleotide conjugate molecules sufficient to create a lipid micelle comprising lipid-oligonucleotide conjugate molecules.