The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2020

Filed:

Feb. 05, 2015
Applicants:

Medimmune, Llc, Gaithersburg, MD (US);

Abbott Laboratories, Abbott Park, IL (US);

Inventors:

Partha S. Chowdhury, Gaithersburg, MD (US);

Reena Varkey, Gaithersburg, MD (US);

Meina Liang, Gaithersburg, MD (US);

Yen-Wah Lee, Gaithersburg, MD (US);

Katie Streicher, Gaithersburg, MD (US);

Koustubh Ranade, Gaithersburg, MD (US);

Ethan Grant, Gaithersburg, MD (US);

Lydia Greenlees, Gaithersburg, MD (US);

Yihong Yao, Gaithersburg, MD (US);

Melissa Parker, Gaithersburg, MD (US);

Gerard Davis, Abbott Park, IL (US);

Nicolette Jeanblanc, Abbott Park, IL (US);

Susan Brophy, Abbott Park, IL (US);

Bruce Dille, Abbott Park, IL (US);

Assignees:

MEDIMMUNE, LLC, Gaithersburg, MD (US);

ABBOTT LABORATORIES, Abbott Park, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C07K 16/18 (2006.01); A61P 11/06 (2006.01); A61P 17/00 (2006.01); A61P 11/00 (2006.01); A61K 9/00 (2006.01); A61K 31/137 (2006.01); A61K 31/56 (2006.01); A61K 31/58 (2006.01); A61K 39/395 (2006.01); C07K 16/24 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6884 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 9/0073 (2013.01); A61K 31/137 (2013.01); A61K 31/56 (2013.01); A61K 31/58 (2013.01); A61K 39/3955 (2013.01); A61P 11/00 (2018.01); A61P 11/06 (2018.01); A61P 17/00 (2018.01); C07K 16/18 (2013.01); C07K 16/244 (2013.01); C07K 16/2866 (2013.01); G01N 33/68 (2013.01); G01N 33/6869 (2013.01); G01N 33/6881 (2013.01); A61K 2039/54 (2013.01); C07K 2317/33 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2319/00 (2013.01); C07K 2319/30 (2013.01); G01N 2800/12 (2013.01); G01N 2800/122 (2013.01); G01N 2800/202 (2013.01); G01N 2800/52 (2013.01);
Abstract

This disclosure provides a robust, sensitive, and specific assay for the detection and measurement of periostin levels in samples obtained from human patients having, or suspected of having an IL-13-mediated disease or disorder. The disclosure further provides novel antiperiostin monoclonal antibodies that recognize at least isoforms 1, 2, 3, 4, 7, and 8 of human periostin, and assay kits comprising one or more of these antibodies.


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