logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10774384 B1

PDFFull Text
Date of Patent:
Sep. 15, 2020

Filed:

Apr. 15, 2016

Mdm2-containing double minute chromosomes and methods therefore

Applicant:

Five3 Genomics, Llc, Santa Cruz, CA (US);

Inventors:

John Zachary Sanborn, Santa Cruz, CA (US);

Charles Joseph Vaske, Santa Cruz, CA (US);

Stephen Charles Benz, Santa Cruz, CA (US);

Assignee:

Five3 Genomics, LLC, Santa Cruz, CA (US);

Attorneys:

Martin Fessenmaier

Umberg Zipser, LLP

Primary Examiner:

Frank W Lu

Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6886 (2018.01); G16B 20/00 (2019.01); G16B 30/00 (2019.01); G16B 40/00 (2019.01); G16H 50/20 (2018.01); C12Q 1/6869 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12Q 1/6869 (2013.01); G16B 20/00 (2019.02); G16B 30/00 (2019.02); G16B 40/00 (2019.02); G16H 50/20 (2018.01); C12Q 2600/106 (2013.01); C12Q 2600/172 (2013.01);
Abstract

Contemplated systems and methods allow for computational genomic analysis using paired-end sequence analysis and split read refinement to thereby identify high-confidence breakpoints associated with high copy numbers and orientation of rearrangements, which is then the basis for full reconstruction of double minutes (DM). In especially preferred aspects, the DM will also include an oncogene or tumor suppressor gene, and/or may be found in blood or blood derived fluids.

Find Patent Forward Citations

Quick Actions:

Sanborn, John. (2020). Mdm2-containing double minute chromosomes and methods therefore (U.S. Patent No. 10774384). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10774384

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…