The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2020

Filed:

May. 14, 2018
Applicant:

Abbott Laboratories, Abbott Park, IL (US);

Inventors:

Jiong Wu, Los Gatos, CA (US);

Emily H. Lin, Cupertino, CA (US);

Jihping Yang, Palo Alto, CA (US);

Assignee:

Abbott Laboratories, Abbott park, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/04 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/04 (2013.01); G01N 33/5094 (2013.01);
Abstract

Herein is provided a simple, reliable and accurate method for cellular analysis on hematology analyzers. In various aspects, the methods provide separation and/or differentiation between red blood cells (RBCs) and white blood cells (WBCs) by utilizing a fluorescent dye to selectively stain WBCs such that they emit stronger fluorescence signals. The method provides optimal detection limits on WBCs and RBCs, thereby allowing analysis of samples with sparse cellular concentrations. As few as one reagent may be used to prepare a single dilution for body fluid analysis, in order to simplify the body fluid analysis. Minimal damage to WBCs is attained using the lysis-free approach described in aspects of the disclosure.


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