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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10774311 B1

PDFFull Text
Date of Patent:
Sep. 15, 2020

Filed:

Aug. 26, 2019

Natural killer cells modified to express membrane-bound interleukin 15 and uses thereof

Applicants:

National University of Singapore, Singapore, SG;

St. Jude Children's Research Hospital, Inc., Memphis, TN (US);

Inventors:

Dario Campana, Singapore, SG;

David Shook, Memphis, TN (US);

Masaru Imamura, Niigata, JP;

Assignees:

National University of Singapore, Singapore, SG;

St. Jude Children's Research Hospital, Inc., Memphis, TN (US);

Attorney:

Hamilton, Brook, Smith & Reynolds, P.C.

Primary Examiner:

Claire Kaufman

Int. Cl.
CPC ...
A61K 38/20 (2006.01); C12N 5/0783 (2010.01); A61K 35/17 (2015.01); C12N 5/00 (2006.01); C12N 15/62 (2006.01); C07K 14/54 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0646 (2013.01); A61K 35/17 (2013.01); A61K 38/2013 (2013.01); A61K 38/2086 (2013.01); C07K 14/5443 (2013.01); C07K 14/70517 (2013.01); C12N 5/0006 (2013.01); C12N 15/62 (2013.01); C07K 2319/03 (2013.01); C12N 2501/2315 (2013.01); C12N 2510/00 (2013.01);
Abstract

The present invention provides, in certain aspects, a natural killer (NK) cell that expresses all or a functional portion of interleukin-15 (IL-15), and methods for producing such cells. The invention further provides methods of using a natural killer (NK) cell that expresses all or a functional portion of interleukin-15 (IL-15) to treat cancer in a subject or to enhance expansion and/or survival of NK cells.

Find Patent Forward Citations

Campana, Dario. (2020). Natural killer cells modified to express membrane-bound interleukin 15 and uses thereof (U.S. Patent No. 10774311). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10774311

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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