The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10774307 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 15, 2020

Filed:

Sep. 29, 2017
Applicant:

Xinyi Wu, Jinan Shandong, CN;

Inventors:

Xinyi Wu, Jinan Shandong, CN;

Lin Shen, Jinan Shandong, CN;

Assignee:

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/079 (2010.01); A61L 27/38 (2006.01); A61L 27/36 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0621 (2013.01); A61L 27/3604 (2013.01); A61L 27/3808 (2013.01); A61L 27/3839 (2013.01); A61L 2430/16 (2013.01); C12N 2500/30 (2013.01); C12N 2500/90 (2013.01); C12N 2501/115 (2013.01); C12N 2502/09 (2013.01); C12N 2506/09 (2013.01); C12N 2509/00 (2013.01);
Abstract

The present invention discloses a method of inducing and differentiating human skin-derived precursors into corneal endothelial-like cells. The present invention utilizes human skin-derived precursors to induce corneal endothelial-like cells that are theoretically close to normal human corneal endothelial cells successfully by co-culturing with B4G12 corneal endothelial cells. Furthermore, the obtained corneal endothelial-like cells are applied to a corneal endothelial decompensation animal model, and corneal endothelium of the animal is successfully repaired, which has an important clinical application prospect.


Find Patent Forward Citations

Wu, Xinyi. (2020). Method of inducing and differentiating human skin-derived precursors to differentiate into corneal endothelial-like cells (U.S. Patent No. 10774307). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10774307

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