The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2020
Filed:
Dec. 19, 2016
Applicant:
Hangzhou Sumgen Biotechnology Co., Ltd., Zhejiang, CN;
Inventor:
Fan Yang, Beijing, CN;
Assignee:
Hangzhou Sumgen Biotechnology Co., Ltd, Zhejiang, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61P 37/04 (2006.01); A61P 35/00 (2006.01); C12N 15/62 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61P 35/00 (2018.01); A61P 37/04 (2018.01); C07K 16/2818 (2013.01); C12N 15/62 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
Disclosed are a human programmed cell death 1 receptor (hPD-1) antibody, a method of preparing the same, and use thereof. The preparation method comprises screening by using a natural antibody library screening platform to obtain a new human programmed cell death 1 receptor antibody. The antibody obtained by the screening step can specifically identify human PD-1 molecules and is used to inhibit mutual interactions between PD-1/PD-L1 and PD-1/PD-L2, thereby improving a level of an immune response.