The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2020
Filed:
Nov. 22, 2017
Applicant:
Daiichi Sankyo Company, Limited, Chuo-ku, Tokyo, JP;
Inventors:
Masahiro Ota, Edogawa-ku, JP;
Hidekazu Inoue, Ota-ku, JP;
Junya Kawai, Ota-ku, JP;
Hitoshi Ohki, Nishitokyo, JP;
Tadashi Toki, Setagaya-ku, JP;
Assignee:
Daiichi Sankyo Company, Limited, Chuo-ku, Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/052 (2006.01); A61K 31/496 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01);
U.S. Cl.
CPC ...
C07D 491/052 (2013.01); A61K 31/496 (2013.01); A61P 35/00 (2018.01); A61P 43/00 (2018.01);
Abstract
Provided is a novel compound or a salt thereof inhibiting MTHFD2 and useful for treating a disease caused by overexpression of MTHFD2, a disease involved in overexpression of MTHFD2 and/or a disease associated with overexpression of MTHFD2. Solution Provided is a sulfonamide derivative having a coumarin skeleton represented by the following formula (I) and having various substituents: wherein R, R, R, R, R, Rand Rare the same as defined in the specification,and a salt thereof.