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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10774083 B1

PDFFull Text
Date of Patent:
Sep. 15, 2020

Filed:

Sep. 14, 2017

Heterocyclic amide compound

Applicant:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Inventors:

Takaharu Hirayama, Kanagawa, JP;

Yasuhiro Hirata, Kanagawa, JP;

Yusuke Tominari, Kanagawa, JP;

Naoki Iwamura, Kanagawa, JP;

Yusuke Sasaki, Kanagawa, JP;

Moriteru Asano, Tokushima, JP;

Terufumi Takagi, Kanagawa, JP;

Masanori Okaniwa, Cambridge, MA (US);

Shinichi Imamura, Kanagawa, JP;

Assignee:

TAKEDA PHARMACEUTICAL COMPANY LIMITED, Osaka, JP;

Attorney:

Wenderoth, Lind & Ponack, L.L.P.

Primary Examiner:

Brian E McDowell

Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 473/28 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 409/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 473/40 (2006.01); C07D 519/00 (2006.01); A61P 35/00 (2006.01); A61K 31/506 (2006.01); A61K 31/444 (2006.01); A61K 31/4439 (2006.01); C07D 473/00 (2006.01); C07D 473/32 (2006.01); A61K 31/5377 (2006.01); A61K 31/501 (2006.01); A61K 31/52 (2006.01); A61P 43/00 (2006.01); A61K 31/437 (2006.01); C12N 9/99 (2006.01);
U.S. Cl.
CPC ...
C07D 473/28 (2013.01); A61K 31/437 (2013.01); A61K 31/444 (2013.01); A61K 31/4439 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/52 (2013.01); A61K 31/5377 (2013.01); A61P 35/00 (2018.01); A61P 43/00 (2018.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 473/00 (2013.01); C07D 473/32 (2013.01); C07D 473/40 (2013.01); C07D 519/00 (2013.01); C12N 9/99 (2013.01);
Abstract

Provided is a heterocyclic amide compound that may have a PRS inhibitory action and is expected to be useful as a prophylactic or therapeutic agent for PRS associated diseases and the like including cancer. A compound represented by the following formula (I): wherein a group represented by is a group represented by the following formula (II) or the following formula (III): and other symbols are as described in the DESCRIPTION, or a salt thereof.

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