The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2020
Filed:
Apr. 15, 2016
Applicant:
The Children's Medical Center Corporation, Boston, MA (US);
Inventors:
David A Williams, Dover, MA (US);
Serena De Vita, Boston, MA (US);
Assignee:
Children's Medical Center Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); C07D 413/06 (2006.01); A61K 31/4439 (2006.01); A61K 31/4245 (2006.01); A61P 35/02 (2006.01); A61P 19/08 (2006.01); A61P 29/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61K 31/4245 (2013.01); A61K 31/4439 (2013.01); A61K 45/06 (2013.01); A61P 19/08 (2018.01); A61P 29/00 (2018.01); A61P 35/02 (2018.01); C07D 413/06 (2013.01);
Abstract
This disclosure relates to compositions including certain compounds identified by a quantitative, high throughput assay to be effective in the treatment of a Rac-GTPase mediated disorder (e.g., acute lymphoblastic or chronic myelogenous leukemia), as well as methods for the manufacture of and the use of these compounds for treating a Rac-GTPase mediated disorder.