The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2020
Filed:
Jun. 06, 2019
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Eugenia Trushina, Pine Island, MN (US);
Robert Greenhouse, Newark, CA (US);
Kevin Greenman, Sunnyvale, CA (US);
William Thomas, San Jose, CA (US);
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Abstract
Compounds and compositions that can modulate mitochondrial function in neuronal cells are provided herein, as are methods for using the compounds and compositions to treat or prevent conditions such as Alzheimer's disease. For example, compounds of Formula I, compositions containing the compounds, and methods for using the compounds and compositions are provided herein: wherein X is absent, CH, or C(O); Ris H, OH, CN, NO, halo, Calkyl, Chaloalkyl, Calkoxy, Chaloalkoxy, Ccycloalkyl, amino, Calkylamino, or di(Calkyl)amino; Ris H or Calkyl; Ris H, Calkyl, —C(O)(Calkyl), or —C(O)O(Calkyl); Ris Ccycloalkyl, Caryl, 5-10 membered heteroaryl, or 5-10 membered heterocycloalkyl, each optionally substituted by 1, 2, 3, or 4 independently selected Rgroups; and Ris OH, CN, NO, halo, Calkyl, Chaloalkyl, Calkoxy, Chaloalkoxy, Ccycloalkyl, amino, Calkylamino, or di(Calkyl)amino.