The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 15, 2020

Filed:

Dec. 15, 2015
Applicants:

The Governing Council of the University of Toronto, Toronto, CA;

Sinai Health System, Toronto, CA;

Inventors:

Benjamin J. Blencowe, Toronto, CA;

Mathieu Quesnel-Vallieres, Scarborough, CA;

Manuel Irimia, Barcelona, ES;

Bushra Raj, Calgary, CA;

Sabine P. Cordes, Toronto, CA;

Assignees:

The Governing Council of the University of Toronto, Toronto, Ontario, CA;

Sinai Health System, Toronto, Ontario, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/55 (2006.01); A61K 38/05 (2006.01); A61K 31/7088 (2006.01); G01N 33/68 (2006.01); C12Q 1/6883 (2018.01); A61K 38/46 (2006.01); G01N 33/50 (2006.01); A01K 67/027 (2006.01); C07K 14/47 (2006.01); A61K 45/06 (2006.01); A61K 31/713 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/05 (2013.01); A01K 67/0276 (2013.01); A01K 67/0278 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 38/46 (2013.01); A61K 38/55 (2013.01); A61K 45/06 (2013.01); A61K 49/0008 (2013.01); C07K 14/4702 (2013.01); C12Q 1/6883 (2013.01); G01N 33/5058 (2013.01); G01N 33/5088 (2013.01); G01N 33/6896 (2013.01); A01K 2217/052 (2013.01); A01K 2217/072 (2013.01); A01K 2217/077 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0306 (2013.01); A01K 2267/0356 (2013.01); C12Q 2600/156 (2013.01); G01N 2800/28 (2013.01);
Abstract

Methods for treatment and diagnosis of neurological disorders such as autism and autism spectrum disorder are disclosed. Also disclosed are modulators of alternative splicing regulators SRRM4 and/or SRRM3 for treating neurological disorders. Further disclosed are agents that modulate the expression of at least one splice variant for treating neurological disorders. Mouse models of neurological disorders having increased or decreased expression of SRRM4 and/or SRRM3 are also disclosed.


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Blencowe, Benjamin. (2020). Modulation and detection of a neuronal alternative splicing regulatory network for treatment and diagnosis of neurological disorders (U.S. Patent No. 10772928). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10772928

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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