The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 15, 2020
Filed:
Mar. 14, 2018
Applicant:
Les Hopitaux Universitaires DE Geneve, Geneva, CH;
Inventor:
Rastine Mérat, Duingt, FR;
Assignee:
LES HOPITAUX UNIVERSITAIRES DE GENEVE, Geneva, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/435 (2006.01); A61K 33/14 (2006.01); A61K 31/437 (2006.01); A61P 35/00 (2006.01); A61K 33/00 (2006.01); G01N 33/50 (2006.01); A61K 31/4439 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
A61K 31/437 (2013.01); A61K 33/00 (2013.01); A61P 35/00 (2018.01); G01N 33/5011 (2013.01); A61K 31/4439 (2013.01); A61K 31/506 (2013.01);
Abstract
The present invention relates to agents enhancing HuR/ELAV levels for use in the treatment of BRAF-mutated cancers and uses thereof. In particular, the invention relates to the use of agents enhancing HuR/ELAV levels in combination with BRAF inhibitors for the treatment of BRAF-mutated cancers, in particular melanoma and to methods for identifying agents useful for potentiating the effects of BRAF inhibitors, when used in combination.