The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2020

Filed:

Oct. 26, 2011
Applicants:

Lawrence Charles Lapointe, North Ryde, AU;

Susanne Kartin Pedersen, North Ryde, AU;

Aidan Mcevoy, North Ryde, AU;

Inventors:

Lawrence Charles LaPointe, North Ryde, AU;

Susanne Kartin Pedersen, North Ryde, AU;

Aidan McEvoy, North Ryde, AU;

Assignee:

CLINICAL GENOMICS PTY LTD, Elsternwick, Victoria, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6806 (2018.01); G01N 33/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6806 (2013.01);
Abstract

The present invention relates to a method of enriching for membranous microvesicles relative to the cellular population in a biological sample. More particularly, there is provided a method for enriching for exosomes from plasma. In a related aspect, there is provided a method of reducing the concentration of cellular and cellular derived molecules in a biological sample. Still further, the present invention provides methods for selectively isolating mRNA subpopulations from exosomes. Yet further, there are provided methods of amplifying exosome derived RNA. The method of the present invention is useful in a range of applications including, but not limited to, diagnostic, prognostic, therapeutic, research and development applications, to the extent that the enrichment of exosomes is required.


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