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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10767186 B1

PDFFull Text
Date of Patent:
Sep. 08, 2020

Filed:

Aug. 10, 2016

Organic compounds

Applicant:

Novartis Ag, Basel, CH;

Inventors:

Yehuda G. Assaraf, D.n. Misgav, IL;

Thomas Jostock, Neuenburg am Rhein, DE;

Hans-Peter Knopf, Schallstadt, DE;

Assignee:

Novartis AG, Basel, CH;

Attorney:

Linyu L. Mitra

Primary Examiner:

Celine X Qian

Int. Cl.
CPC ...
C12N 15/85 (2006.01); C12N 15/64 (2006.01); C07K 14/705 (2006.01); C12N 15/10 (2006.01); C07K 16/00 (2006.01); C12N 15/65 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/64 (2013.01); C07K 14/705 (2013.01); C07K 16/00 (2013.01); C12N 15/1079 (2013.01); C12N 15/65 (2013.01); C12N 15/85 (2013.01); C12P 21/00 (2013.01); C07K 2317/14 (2013.01);
Abstract

The present invention relates to a novel selection system for use in a eukaryotic cell culture process and for expression of a recombinant product of interest. The selection system is based on the introduction of an exogenous functional membrane-bound folate receptor gene together with the polynucleotide or gene encoding the product of interest into a eukaryotic cell and can be widely utilized with eukaryotic cells for which cellular viability is dependent upon folic acid uptake.

Find Patent Forward Citations

Assaraf, Yehuda. (2020). Organic compounds (U.S. Patent No. 10767186). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10767186

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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