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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10766961 B1

PDFFull Text
Date of Patent:
Sep. 08, 2020

Filed:

Aug. 11, 2015

Anti-vegfr2 antibody therapy for hepatocellular carcinoma

Applicant:

Imclone, Llc, Indianapolis, IN (US);

Inventors:

Paolo B. Abada, Indianapolis, IN (US);

Shao-Chun Chang, Carmel, IN (US);

Yanzhi Hsu, Basking Ridge, NJ (US);

Ling Yang, Bridgewater, NJ (US);

Assignee:

ImClone LLC, Indianapolis, IN (US);

Attorney:

Margaret Tomaska

Primary Examiner:

Hong Sang

Int. Cl.
CPC ...
G01N 33/574 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); A61P 35/00 (2018.01); G01N 33/57438 (2013.01); A61K 39/395 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55 (2013.01); C07K 2317/21 (2013.01); G01N 2333/47 (2013.01); G01N 2800/52 (2013.01);
Abstract

The invention provides for a human antibody that binds to human vascular endothelial growth factor receptor 2, preferably ramucirumab, for the treatment of hepatocellular carcinoma (HCC) in patients having levels of alpha-fetoprotein (AFP) of 1.5×ULN (Upper Limit of Normal) or greater, and as a predictive method for the treatment of HCC in patients having AFP levels of 1.5×ULN or greater.

Find Patent Forward Citations

Abada, Paolo. (2020). Anti-vegfr2 antibody therapy for hepatocellular carcinoma (U.S. Patent No. 10766961). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10766961

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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