The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2020

Filed:

Apr. 05, 2017
Applicant:

The University of Kansas, Lawrence, KS (US);

Inventor:

Blake R. Peterson, Lawrence, KS (US);

Assignee:

The University of Kansas, Lawrence, KS (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 7/08 (2006.01); C07K 16/32 (2006.01); A61K 47/54 (2017.01); A61K 47/65 (2017.01); A61K 47/68 (2017.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 47/554 (2017.08); A61K 47/65 (2017.08); A61K 47/6811 (2017.08); A61K 47/6849 (2017.08); A61K 47/6851 (2017.08); A61K 47/6889 (2017.08); C07K 16/2887 (2013.01); C07K 16/32 (2013.01); C07K 2317/24 (2013.01); C07K 2317/73 (2013.01); C07K 2319/06 (2013.01); C07K 2319/74 (2013.01);
Abstract

A peptide can have a sequence of one of SEQ ID NOs: 78-91. A conformationally-constrained kinked peptide includes: a conformationally-constraining portion and a kinked portion linked to the conformationally-constraining portion that conformationally constrains the kinked portion having a peptide sequence of one of SEQ NOs: 78-97. A cell-targeting compound can include a conformationally-constrained kinked peptide having a peptide sequence of one of SEQ ID NOs: 78-97. The peptide sequence can be one of SEQ ID NOs: 78-97, or 78-91, or 92-97. A cell-targeting compound can include a conformationally-constrained kinked peptide linked to a branched linker with one branch arm linked to a specific targeting moiety and one branch arm linked to a general targeting moiety. The specific targeting moiety can be an antibody. The general targeting moiety can be a lipid or cholesterol derivative.


Find Patent Forward Citations

Loading…