The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2020
Filed:
Apr. 11, 2017
Applicant:
Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US);
Inventors:
Ruben Vardanyan, Tucson, AZ (US);
Victor Hruby, Tucson, AZ (US);
Assignee:
Arizona Board of Regents on behalf of the University of Arizona, Tucson, AZ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/58 (2006.01); C07K 4/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 4/00 (2013.01); C07D 211/58 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention provides compounds that can modulate opioid receptors. Some compounds of the invention are modulators of μ- and/or δ-opioid receptors. Still other compounds of the invention are opioid receptor antagonists. Some compounds of the invention can modulate opioid receptors with a significantly less likelihood of developing addiction or abuse compared to conventional opioid ligands, such as morphine. In particular, compounds of the invention are of the formula: wherein