The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2020
Filed:
Feb. 27, 2015
Applicant:
Nantbioscience, Inc., Culver City, CA (US);
Inventors:
Chunlin Tao, Newport Coast, CA (US);
Qinwei Wang, Alhambra, CA (US);
Laxman Nallan, Rancho Mission Viejo, CA (US);
David Ho, Monterey Park, CA (US);
Tulay Polat, Tustin, CA (US);
Forrest Arp, Irvine, CA (US);
Paul Weingarten, Anaheim, CA (US);
Assignee:
NANTBIOSCIENCE, INC., Culver City, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); A61K 31/506 (2006.01); A61P 37/00 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 417/14 (2006.01); C07D 487/04 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); A61P 29/00 (2018.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 417/14 (2013.01); C07D 487/04 (2013.01);
Abstract
The present invention provides antitumor agents comprising substituted pyrimidine derivatives and pharmaceutically-acceptable formulations thereof, methods for making novel compounds and methods for using the compounds. The compounds and compositions in accordance with the invention have utility in treatment of a variety of diseases and have kinase inhibitory activities.