The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2020

Filed:

Jan. 09, 2015
Applicant:

Transgene SA, Illkirch Graffenstaden, FR;

Inventors:

Jean-Baptiste Marchand, Obernai, FR;

Nathalie Silvestre, Ergersheim, FR;

François Penin, Decines, FR;

Assignee:

TRANSGENE SA, Illkirch Graffenstaden, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/02 (2006.01); A61K 39/04 (2006.01); C07H 21/00 (2006.01); C07K 14/35 (2006.01); C07K 16/12 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 39/04 (2013.01); A61K 45/06 (2013.01); C07K 14/35 (2013.01); C07K 16/1289 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/53 (2013.01); A61K 2039/57 (2013.01); C07K 2317/34 (2013.01); C07K 2319/00 (2013.01); C07K 2319/035 (2013.01); C12N 2710/24141 (2013.01);
Abstract

The present invention relates generally to novel immunogenic combinations comprising or encoding at least two heterooligomeric mycobacterial antigens and preferably a fusion polypeptide comprising said two heterooligomeric mycobacterial antigens, where the mycobacterial antigens are selected from the group of Esx, PE and PPE antigens of aspecies, particularly aof the tuberculosis complex such as(Mtb). The present invention also relates to vectors, host cells and compositions comprising or encoding said immunogenic combination as well as to methods for expressing and producing it. The present invention also relates to methods of using said immunogenic combination, fusion polypeptide, vector, host cell, composition particularly for inducing or stimulating an immune response with the goal of providing a protective response against ainfection or any disease caused by or associated with ainfection.


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