The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2020

Filed:

Dec. 08, 2015
Applicants:

Sapporo Medical University, Sapporo-shi, Hokkaido, JP;

Sumitomo Dainippon Pharma Co., Ltd., Osaka-shi, Osaka, JP;

Inventors:

Noriyuki Sato, Sapporo, JP;

Toshihiko Torigoe, Sapporo, JP;

Yoshihiko Hirohashi, Sapporo, JP;

Takayuki Kanaseki, Sapporo, JP;

Sho Miyamoto, Sapporo, JP;

Vitaly Kochin, Sapporo, JP;

Masashi Goto, Osaka, JP;

Assignees:

Sapporo Medical University, Sapporo-shi, Hokkaido, JP;

Sumitomo Dainippon Pharma Co., Ltd., Osaka-shi, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 39/00 (2006.01); C07K 16/30 (2006.01); A61K 48/00 (2006.01); C12Q 1/68 (2018.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01); A61P 35/00 (2006.01); C07K 14/47 (2006.01); C07K 7/06 (2006.01); C07K 16/28 (2006.01); C12N 5/0783 (2010.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 39/00118 (2018.08); A61K 48/00 (2013.01); A61P 35/00 (2018.01); C07K 7/06 (2013.01); C07K 14/47 (2013.01); C07K 14/4748 (2013.01); C07K 16/2833 (2013.01); C07K 16/30 (2013.01); C12N 5/0638 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5011 (2013.01); G01N 33/5088 (2013.01); G01N 33/574 (2013.01); G01N 33/57484 (2013.01); A61K 2039/572 (2013.01); A61K 2039/82 (2018.08); C07K 2317/34 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01); G01N 2333/46 (2013.01); G01N 2333/70539 (2013.01);
Abstract

The purpose of the present invention is to provide: a detection agent for specifically detecting a cancer stem cell; a tumor antigen peptide specifically presented by cancer stem cells; a medicinal composition useful in preventing and/or treating cancer, said medicinal composition comprising the aforementioned tumor antigen peptide as an active ingredient; a method for screening the tumor antigen peptide; etc. To achieve the above-mentioned purpose, provided are: peptides represented by Y-X-Z; a polyepitope peptide consisting of a plurality of epitope peptides connected together, said polyepitope peptide containing at least one of the above-mentioned peptides as one of the epitope peptides; a polynucleotide encoding the aforementioned peptides and/or polyepitope peptide; a medicinal composition comprising the same as an active ingredient; a prophylactic and/or therapeutic agent for cancer characterized by inducing CTL; etc.


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