The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2020

Filed:

Jul. 26, 2018
Applicant:

Nortic Holdings Inc., East Brunswick, NJ (US);

Inventors:

S. George Kottayil, West Windsor, NJ (US);

Amresh Kumar, Plainsboro, NJ (US);

Prasanna Sunthankar, West Windsor, NJ (US);

Vimal Kavuru, Holmdel, NJ (US);

Assignee:

NORTIC HOLDINGS INC., East Brunswick, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/455 (2006.01); A61K 31/4422 (2006.01); A61K 47/10 (2017.01); A61K 47/24 (2006.01); A61K 47/26 (2006.01); A61K 47/44 (2017.01); A61K 9/00 (2006.01); A61K 9/107 (2006.01);
U.S. Cl.
CPC ...
A61K 31/455 (2013.01); A61K 9/0019 (2013.01); A61K 9/1075 (2013.01); A61K 31/4422 (2013.01); A61K 47/10 (2013.01); A61K 47/24 (2013.01); A61K 47/26 (2013.01); A61K 47/44 (2013.01);
Abstract

A nimodipine injection concentrate and diluted formulation comprises nimodipine (base or salt), an effective amount of a hydrophilic surfactant, and a pharmaceutically acceptable carrier for injection which is an aqueous solution, an organic solvent, an oil, or a cyclodextrin, such that the nimodipine is substantially contained in a concentrated injection solution, suspension, emulsion or complex as a micelle or a colloidal particle or an inclusion complex and the formulation is stable and clear. In certain embodiments, the hydrophilic surfactant is polysorbate 80.


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