The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2020
Filed:
Dec. 29, 2017
Enzychem Lifesciences Corporation, Daejeon, KR;
Korea Research Institute of Bio Science and Biotechnology, Daejeon, KR;
Sei-Ryang Oh, Daejeon, KR;
Kyung Seop Ahn, Daejeon, KR;
Su Ui Lee, Daejeon, KR;
In Sik Shin, Daejeon, KR;
Ok-Kyoung Kwon, Daejeon, KR;
Seung Hyung Kim, Daejeon, KR;
Chan Mi Chun, Daejeon, KR;
Tae-Suk Lee, Daejeon, KR;
Yong-Hae Han, Seoul, KR;
Ki Young Sohn, Seoul, KR;
JongKoo Kang, Chungcheongbuk-do, KR;
Hye Kyung Kim, Seoul, KR;
Enzychem Lifesciences Corporation, Daejeon, KR;
Korea Research Institute of BioScience and Biotechnology, Daejeon, KR;
Abstract
The present invention relates to a pharmaceutical composition containing a monoacetyldiacylglycerol compound as an active ingredient for preventing or treating chronic obstructive pulmonary diseases, and a functional health food composition for treating or preventing chronic obstructive pulmonary diseases. The monoacetyldiacylglycerol compound of the present invention inhibits the IL-4 expression in EL-4 cells and inhibits the infiltration of inflammatory cells into the bronchial tube in an animal model. In addition, the compounds of the present invention have an excellent effect of inhibiting the expression of CXCL-1, TNF-α, or MIP-2, thereby overcoming side effects of the currently used therapeutic agents for chronic obstructive pulmonary diseases, having no toxicity, and exhibiting a superior therapeutic effect, and thus can be useful as a composition for preventing, treating, and alleviating chronic obstructive pulmonary diseases.