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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10765624 B1

PDFFull Text
Date of Patent:
Sep. 08, 2020

Filed:

Mar. 13, 2019

Amino-pyrimidine skeletal muscle modulators

Applicant:

Cytokinetics, Inc., South San Francisco, CA (US);

Inventors:

Zhe Yang, Daly City, CA (US);

Alex R. Muci, South San Francisco, CA (US);

Jeffrey Warrington, San Mateo, CA (US);

Gustave Bergnes, Pacifica, CA (US);

Bradley P. Morgan, Oakland, CA (US);

Chihyuan Chuang, Millbrae, CA (US);

Antonio Romero, San Mateo, CA (US);

Scott Collibee, San Carlos, CA (US);

Xiangping Qian, Foster City, CA (US);

Pu-Ping Lu, Foster City, CA (US);

Assignee:

CYTOKINETICS, INC., South San Francisco, CA (US);

Attorney:

Morrison & Foerster LLP

Primary Examiner:

Alexander R Pagano

Assistant Examiner:

Ebenezer O Sackey

Int. Cl.
CPC ...
A61K 9/00 (2006.01); C07D 403/04 (2006.01); C07D 239/42 (2006.01); C07D 513/04 (2006.01); C07D 495/04 (2006.01); C07D 471/04 (2006.01); C07D 417/04 (2006.01); C07D 413/14 (2006.01); C07D 409/14 (2006.01); C07D 401/14 (2006.01); C07D 401/12 (2006.01); C07D 239/48 (2006.01); C07D 403/10 (2006.01); C07D 401/04 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0014 (2013.01); A61K 9/006 (2013.01); A61K 9/007 (2013.01); A61K 9/0019 (2013.01); A61K 9/0034 (2013.01); A61K 9/0043 (2013.01); A61K 9/0048 (2013.01); A61K 9/0053 (2013.01); C07D 239/42 (2013.01); C07D 239/48 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/10 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 495/04 (2013.01); C07D 513/04 (2013.01);
Abstract

Provided are compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R, R, R, R, R, R, R, R, R, X and m are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula I, or a pharmaceutically acceptable salt thereof.

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