The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 08, 2020

Filed:

Oct. 19, 2017
Applicants:

Technische Universiteit Eindhoven, Eindhoven, NL;

Rwth Aachen, Aachen, DE;

Inventors:

Corrinus Cornelis van Donkelaar, Eindhoven, NL;

Keita Ito, Helmond, NL;

Tim Bolle, Aachen, DE;

Assignees:

Technische Universiteit Eindhoven, Eindhoven, NL;

RWTH Aachen, Aachen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/30 (2006.01); A61L 27/52 (2006.01); A61L 27/50 (2006.01); A61L 27/58 (2006.01);
U.S. Cl.
CPC ...
A61F 2/30756 (2013.01); A61L 27/50 (2013.01); A61L 27/52 (2013.01); A61F 2002/30761 (2013.01); A61F 2002/30766 (2013.01); A61L 27/58 (2013.01);
Abstract

An artificial cartilage is provided whereby a fixed negative charged hydrogel has been infused within a restrictive swelling network, which limits and restricts the thickness of the artificial cartilage. At least 60% of the volume of the artificial cartilage is composed of the restricted and swollen hydrogel. The restrictive swelling network restricts the hydrogel to swell not more than 10% with respect to its maximum swelling capacity, i.e. a swelling capacity to swell 10-fold more is retained. The hydrogel within the restrictive swelling network has an equilibrium stiffness between 0.5 and 2 MPa to resist external loads applied to the top surface layer or the bottom surface layer of the artificial cartilage. The hydrogel has a fixed negative charge density of −0.17 to −0.23 mEg/ml and is capable of swelling between 2-15 times compared to the volume of the hydrogel without being restricted.


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