The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 08, 2020
Filed:
Apr. 07, 2015
University of Rochester, Rochester, NY (US);
Edward Bernard Brown, III, Honeoye Falls, NY (US);
Seth Warrington Perry, Pittsford, NY (US);
Kathleen Anne Burke, Rockville Centre, NY (US);
Robert Matthew Kottmann, Rochester, NY (US);
Patricia Janet Sime, Pittsford, NY (US);
Jesse Wakefield Sharp, Rochester, NY (US);
University of Rochester, Rochester, NY (US);
Abstract
A method and apparatus for determining the progressive potential of a disease is disclosed. The forward to backward propagating second harmonic generation signal derived from a second harmonic generation instrument is used to assess the collagen microstructure of imaged body tissue by way of numerical values that are in turn used to determine the progressive or metastatic potential of the disease. The disease may, for example, be a cancer such as breast cancer, lung fibrosis, colorectal adenocarcinoma, or the like. The apparatus may include in vivo instruments or laboratory diagnostic instruments with methods disclosed herein.