The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2020

Filed:

Jan. 07, 2016
Applicants:

Nottingham University Hospitals Nhs Trust, Nottingham, Nottinghamshire, GB;

The University of Nottingham, Nottingham, Nottinghamshire, GB;

Inventors:

Mark Devonald, Nottingham, GB;

David Gardner, Nottingham, GB;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); G01N 33/84 (2006.01); G01N 33/68 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
G01N 33/84 (2013.01); G01N 33/6893 (2013.01); G01N 33/6896 (2013.01); G01N 21/648 (2013.01); G01N 2800/085 (2013.01); G01N 2800/347 (2013.01);
Abstract

The present invention provides a method for diagnosing in a subject Acute Kidney Injury or a related or analogous disease state. The method comprises the steps of a) providing a sample taken from the subject: b) analysing the sample from the subject to determine the level of a biomarker selected from certain atomic species; and c) comparing the level of the biomarker in the sample to a reference level of the biomarker that is characteristic of a healthy subject, eg a subject having normal renal function. An elevated level of the biomarker in the sample relative to the reference level is indicative of Acute Kidney Injury or a related or analogous disease state. The invention also relates to the use of an atomic species selected from those in Table 1 as a biomarker for Acute Kidney Injury or a related or analogous disease state, and test kits comprising an analytical element sensitive to those biomarkers.


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