The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2020
Filed:
Jul. 09, 2018
Applicant:
Pain Therapeutics, Inc., Austin, TX (US);
Inventors:
Hoau-Yan Wang, Philadelphia, PA (US);
Lindsay Burns Barbier, Austin, TX (US);
Assignee:
Cassava Science, Inc., Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/079 (2010.01); C07D 265/30 (2006.01); C07D 211/14 (2006.01); C07D 277/04 (2006.01); C07D 295/088 (2006.01); C07D 205/04 (2006.01); C07D 491/056 (2006.01); C07D 498/10 (2006.01); C07D 217/04 (2006.01); C07D 471/10 (2006.01); C07D 491/04 (2006.01); C07D 207/08 (2006.01); C07D 265/36 (2006.01); C07D 277/02 (2006.01); C07D 279/12 (2006.01); C07D 295/08 (2006.01); C07D 211/74 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0622 (2013.01); C07D 205/04 (2013.01); C07D 207/08 (2013.01); C07D 211/14 (2013.01); C07D 211/74 (2013.01); C07D 217/04 (2013.01); C07D 265/30 (2013.01); C07D 265/36 (2013.01); C07D 277/02 (2013.01); C07D 277/04 (2013.01); C07D 279/12 (2013.01); C07D 295/08 (2013.01); C07D 295/088 (2013.01); C07D 471/10 (2013.01); C07D 491/04 (2013.01); C07D 491/056 (2013.01); C07D 498/10 (2013.01);
Abstract
A method of inhibiting phosphorylation of the tau protein and/or a TLR4-mediated immune response is disclosed. The method contemplates administering to cells in recognized need thereof such as cells of the central nervous system an effective amount of a of a compound or a pharmaceutically acceptable salt thereof that binds to a pentapeptide of filamin A (FLNA) of SEQ ID NO: 1, and contains at least four of the six pharmacophores of FIGS.-