The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2020

Filed:

Nov. 05, 2013
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Zev Jordan Gartner, San Francisco, CA (US);

Jennifer S. Liu, San Francisco, CA (US);

Noel Youngho Jee, San Francisco, CA (US);

Michael E. Todhunter, San Francisco, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); G01N 33/53 (2006.01); C12N 5/00 (2006.01); C12N 11/06 (2006.01); C12N 11/00 (2006.01); C12N 5/07 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0068 (2013.01); C12N 11/00 (2013.01); C12N 11/06 (2013.01); B01J 2219/0063 (2013.01); B01J 2219/00612 (2013.01); B01J 2219/00617 (2013.01); B01J 2219/00626 (2013.01); B01J 2219/00659 (2013.01); B01J 2219/00722 (2013.01); B01J 2219/00743 (2013.01); C12N 2533/00 (2013.01); C12N 2535/10 (2013.01);
Abstract

The present disclosure provides methods of patterning cells on a surface of a substrate. The methods include disposing a pattern of nucleic acids on a surface of a substrate, and contacting the patterned nucleic acids under hybridization conditions with a first suspension of cells, where cells of the first suspension include cell surface-attached nucleic acids complementary to the patterned nucleic acids, and where the cell surface-attached nucleic acids hybridize to the patterned nucleic acids to pattern the cells on the surface of the substrate. Systems and kits for practicing the methods are also provided.


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