The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 01, 2020

Filed:

Oct. 16, 2015
Applicant:

The University of Chicago, Chicago, IL (US);

Inventors:

Anthony A. Kossiakoff, Chicago, IL (US);

Lucas J. Bailey, Chicago, IL (US);

Assignee:

The University of Chicago, Chicago, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 17/00 (2006.01); C07K 14/315 (2006.01); C07K 1/22 (2006.01); C07K 16/00 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
C07K 14/315 (2013.01); C07K 1/22 (2013.01); C07K 16/00 (2013.01); C07K 17/00 (2013.01); G01N 33/54353 (2013.01); C07K 2317/55 (2013.01); C07K 2319/00 (2013.01); C07K 2319/01 (2013.01); C07K 2319/70 (2013.01); G01N 2333/315 (2013.01);
Abstract

Methods and compositions are provided concerning polypeptides with modifications that increase its binding affinity for the Fab region of an antibody. Methods include using the polypeptides for isolating, detecting, purifying, measuring and quantifying Fab polypeptides. Other embodiments concern kits, compositions, and solid supports containing the polypeptides and for using the polypeptides for isolating, detecting, purifying, measuring and quantifying Fab polypeptide.


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