The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 01, 2020
Filed:
Jun. 07, 2017
Ustav Organicke Chemie a Biochemie Av Cr, V.v.i., Prague, CZ;
Ustav Molekularni Genetiky Akademie Ved Cr, V.v.i., Prague, CZ;
Univerzita Palackeho V Olomouci, Olomouc, CZ;
Helmholtz Zentrum Munchen, Neuherberg, DE;
Martin Kotora, Prague, CZ;
Eva Prchalova, Prague, CZ;
Jerzy Adamski, Munich, DE;
Gabriele Moeller, Munich, DE;
Ondrej Stepanek, Liberec, CZ;
Petr Bartunek, Prague, CZ;
David Sedlak, Prague, CZ;
Marian Hajduch, Moravsky Beroun, CZ;
Petr Dzubak, Brodek u Prerova, CZ;
USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I., Prague, CZ;
USTAV MOLEKULARNI GENETIKY AKADEMIE VED CR, V.V.I., Prague, CZ;
UNIVERZITA PALACKEHO V OLOMOUCI, Olomouci, CZ;
HELMHOLTZ ZENTRUM MUNCHEN, Neuherberg, DE;
Abstract
15β-substituted derivatives of estrone of general formula I wherein R, R, R, R, Rare independently selected from the group consisting of: C-Calkyl, C-Calkoxy, C-Chalogenalkyl, halogen, COORwherein Ris C-Calkyl; H, OH; optionally, R, Rand Rare each formed by a hydrogen atom, while Rand Rtogether form an aryl group, preferably naphthyl, in which the aromatic ring in position C-15 can be mono-, di-, tri-, tetra- and penta-substituted with substituents R-R. Compounds of the invention may be used for diagnosis and possibly also for the treatment of estrogen-dependent diseases.